GDNF 蛋白
(Glial Cell Line Derived Neurotrophic Factor (GDNF))
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| GDNF Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GDNF 蛋白 | 大鼠 | 大肠杆菌（E. Coli） |
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| GDNF 蛋白 | 小鼠 | 大肠杆菌（E. Coli） |
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| GDNF 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 79-217) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- CC (Cell Culture: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
- 生物活性
- Active
Latest Publications for our GDNF 蛋白
: "A bioenergetic shift is required for spermatogonial differentiation." in: Cell discovery, Vol. 6, pp. 56, (2020) (PubMed).
: "The morphological and molecular changes of brain cells exposed to direct current electric field stimulation." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 18, Issue 5, (2015) (PubMed).
: "Multiple astrocyte transcripts encode nigral trophic factors in rat and human." in: Experimental neurology, Vol. 130, Issue 2, pp. 387-93, (1995) (PubMed).
: "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." in: Science (New York, N.Y.), Vol. 260, Issue 5111, pp. 1130-2, (1993) (PubMed).
: "The morphological and molecular changes of brain cells exposed to direct current electric field stimulation." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 18, Issue 5, (2015) (PubMed).
: "Multiple astrocyte transcripts encode nigral trophic factors in rat and human." in: Experimental neurology, Vol. 130, Issue 2, pp. 387-93, (1995) (PubMed).
: "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." in: Science (New York, N.Y.), Vol. 260, Issue 5111, pp. 1130-2, (1993) (PubMed).
Aliases for GDNF 蛋白
glial cell derived neurotrophic factor (Gdnf) 蛋白glial cell derived neurotrophic factor a (gdnfa) 蛋白
glial cell derived neurotrophic factor (GDNF) 蛋白
glial cell line derived neurotrophic factor (Gdnf) 蛋白
glial cell derived neurotrophic factor L homeolog (gdnf.L) 蛋白
AI385739 蛋白
ATF1 蛋白
ATF2 蛋白
gdnf 蛋白
GDNF 蛋白
gdnfa 蛋白
hfb1-gdnf 蛋白
HFB1-GDNF 蛋白
HSCR3 蛋白
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