Retinoblastoma Protein (Rb) 抗体
(Retinoblastoma Protein (Rb Protein))
Controls the progression of the cell cycle from G1 to S phase. Acts through the modulation of E2F action in response to D- type cyclins. Negative regulator of cell proliferation during leaf and gametophyte development. At later stages of development, restricts the progression through additional endocycles. Regulates the root stem cell pool size. Interaction with mastrevirus RepA or nanovirus Clink protein disrupts the RBR/E2F interaction and releases the transcription of replicative enzymes needed by the virus by increasing the E2F DNA-binding activity.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Retinoblastoma Protein (Rb) 抗体 (pSer249, pThr252) | 人 | 兔 Polyclonal |
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| Retinoblastoma Protein (Rb) 抗体 (pSer612) | 人 | 兔 Polyclonal |
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| Retinoblastoma Protein (Rb) 抗体 (pThr821) | 人 | 兔 Polyclonal |
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| Retinoblastoma Protein (Rb) 抗体 (cleaved) | 人 | 小鼠 Monoclonal |
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| Retinoblastoma Protein (Rb) 抗体 (pSer788) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Retinoblastoma Protein (Rb) 抗体 (AA 600-620) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant Retinoblastoma Protein (Rb) 抗体 (full length) | 人 | 兔 Monoclonal |
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| Recombinant Retinoblastoma Protein (Rb) 抗体 (full length) | 人 | 兔 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pSer249, pThr252
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pSer612
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pThr821
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4H246
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- cleaved
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 756-805, pSer788
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 600-620
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- RB1-7080R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- full length
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- RB1-7080R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- full length
Latest Publications for our Retinoblastoma Protein (Rb) 抗体
: "IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1445-1450, (2018) (PubMed).
: "Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus." in: The international journal of biochemistry & cell biology, Vol. 65, pp. 104-12, (2016) (PubMed).
: "High-throughput screening for the identification of small-molecule inhibitors of retinoblastoma protein phosphorylation in cells." in: Analytical biochemistry, Vol. 320, Issue 1, pp. 66-74, (2003) (PubMed).
: "Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein." in: Molecular biology of the cell, Vol. 13, Issue 12, pp. 4401-13, (2002) (PubMed).
: "Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing." in: Oncogene, Vol. 7, Issue 7, pp. 1445-51, (1992) (PubMed).
: "Structure and partial genomic sequence of the human retinoblastoma susceptibility gene." in: Gene, Vol. 80, Issue 1, pp. 119-28, (1989) (PubMed).
: "Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 24, pp. 9059-63, (1988) (PubMed).
: "The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity." in: Nature, Vol. 329, Issue 6140, pp. 642-5, (1987) (PubMed).
: "Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus." in: The international journal of biochemistry & cell biology, Vol. 65, pp. 104-12, (2016) (PubMed).
: "High-throughput screening for the identification of small-molecule inhibitors of retinoblastoma protein phosphorylation in cells." in: Analytical biochemistry, Vol. 320, Issue 1, pp. 66-74, (2003) (PubMed).
: "Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein." in: Molecular biology of the cell, Vol. 13, Issue 12, pp. 4401-13, (2002) (PubMed).
: "Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing." in: Oncogene, Vol. 7, Issue 7, pp. 1445-51, (1992) (PubMed).
: "Structure and partial genomic sequence of the human retinoblastoma susceptibility gene." in: Gene, Vol. 80, Issue 1, pp. 119-28, (1989) (PubMed).
: "Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 24, pp. 9059-63, (1988) (PubMed).
: "The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity." in: Nature, Vol. 329, Issue 6140, pp. 642-5, (1987) (PubMed).
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