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Recombinant Retinoblastoma Protein (Rb) 抗体 (full length)

The 兔 单克隆 anti-Retinoblastoma Protein (Rb) antibody is suitable to detect Retinoblastoma Protein (Rb) in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7878912
发货至: 中国
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Quick Overview for Recombinant Retinoblastoma Protein (Rb) 抗体 (full length) (ABIN7878912)

抗原

See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Retinoblastoma Protein (Rb) antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RB1-7080R
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    full length

    原理

    Recombinant Retinoblastoma Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant human full-length protein was used as the immunogen for the recombinant Retinoblastoma antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant Retinoblastoma antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant Retinoblastoma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

    别名

    Retinoblastoma

    背景

    Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.

    UniProt

    P06400

    途径

    Mitotic G1-G1/S Phases
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