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RAG1 产品

(Recombination Activating Gene 1 (RAG1))
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases. [provided by RefSeq, Jul 2008].

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Featured RAG1 Categories

RAG1 抗体

High quality antibodies with extensive validation data.

RAG1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RAG1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RAG1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN1098121
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7256274
Quantity 200 μL
Datasheet Datasheet
Reactivity Chicken, Human, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN6746209
Quantity 100 μL
Datasheet Datasheet

Recommended RAG1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969856
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1166578
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1058041
Quantity 96 tests
Datasheet Datasheet

Recommended RAG1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317317
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133069
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094920
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RAG1 Products

Lu, Wu, Feng, Shen, Wang, Fallahi, Li, Yang, Hankey, Zhao, Ganju, Li, Cleveland, Zou: "CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis." in: The Journal of clinical investigation, Vol. 124, Issue 4, pp. 1672-84, (2014) (PubMed).

Zhou, Yu, Chang, Zhang, Zhou, Cammas, Sun: "TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20083-8, (2012) (PubMed).

Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

Silver, Spanopoulou, Mulligan, Baltimore: "Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 13, pp. 6100-4, (1993) (PubMed).

Mombaerts, Iacomini, Johnson, Herrup, Tonegawa, Papaioannou: "RAG-1-deficient mice have no mature B and T lymphocytes." in: Cell, Vol. 68, Issue 5, pp. 869-77, (1992) (PubMed).

Shinkai, Rathbun, Lam, Oltz, Stewart, Mendelsohn, Charron, Datta, Young, Stall: "RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement." in: Cell, Vol. 68, Issue 5, pp. 855-67, (1992) (PubMed).

Chun, Schatz, Oettinger, Jaenisch, Baltimore: "The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system." in: Cell, Vol. 64, Issue 1, pp. 189-200, (1991) (PubMed).

Oettinger, Schatz, Gorka, Baltimore: "RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination." in: Science (New York, N.Y.), Vol. 248, Issue 4962, pp. 1517-23, (1990) (PubMed).

Synonyms and alternative names related to RAG1

recombination activating 1 (Rag1), recombination activating 1 (RAG1), recombination activating gene 1 (RAG1), recombination activating gene 1 (rag1), recombination activating gene 1 (Rag1), recombination activating 1 (rag1), recombination activating gene 1 S homeolog (rag1.S), RAG-1, Rag-1, rag-1, rag1, rag1a, RNF74

Protein level used designations for RAG1

  • V(D)J recombination-activating protein 1
  • recombination activation protein 1
  • recombination activating gene 1
  • recombination activating protein 1
  • recombination-activating gene 1
  • recombinase activating protein
  • V(D)J recombination-activating protein 1-like
  • RING finger protein 74
  • recombinase activating gene 1
  • etID309719.25
  • recombinase
  • recombination activating protein
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