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RALBP1 产品

(RalA Binding Protein 1 (RALBP1))

Categories

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin (By similarity).

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Featured RALBP1 Categories

RALBP1 抗体

High quality antibodies with extensive validation data.

RALBP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RALBP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RALBP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (6)
  • (5)
Cat. No. ABIN564745
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Rat
Application WB, IHC, IF, FACS, IHC (p)
Validations
  • (11)
Cat. No. ABIN1500585
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7269840
Quantity 100 μL
Datasheet Datasheet

Recommended RALBP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (5)
Cat. No. ABIN6730973
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1154394
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5706907
Quantity 96 tests
Datasheet Datasheet

Recommended RALBP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317343
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094923
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135513
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RALBP1 Products

Tazat, Harsat, Goldshmid-Shagal, Ehrlich, Henis: "Dual effects of Ral-activated pathways on p27 localization and TGF-? signaling." in: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1812-24, (2013) (PubMed).

Fillatre, Delacour, Van Hove, Bagarre, Houssin, Soulika, Veitia, Moreau: "Dynamics of the subcellular localization of RalBP1/RLIP through the cell cycle: the role of targeting signals and of protein-protein interactions." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 5, pp. 2164-74, (2012) (PubMed).

Neel, Rossman, Martin, Hayes, Yeh, Der: "The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector." in: Molecular and cellular biology, Vol. 32, Issue 8, pp. 1374-86, (2012) (PubMed).

Mollberg, Steinert, Aigner, Hamm, Lin, Elbers, Reissfelder, Weitz, Buchler, Koch: "Overexpression of RalBP1 in colorectal cancer is an independent predictor of poor survival and early tumor relapse." in: Cancer biology & therapy, Vol. 13, Issue 8, pp. 694-700, (2012) (PubMed).

Kidd, Snider, Martin, Graboski, Der, Cox: "Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation." in: International journal of radiation oncology, biology, physics, Vol. 78, Issue 1, pp. 205-12, (2010) (PubMed).

Wu, Owens, Chandra, Popovic, Conaway, Theodorescu: "RalBP1 is necessary for metastasis of human cancer cell lines." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 12, pp. 1003-12, (2010) (PubMed).

Smith, Oxford, Baras, Owens, Havaleshko, Brautigan, Safo, Theodorescu: "Expression of ral GTPases, their effectors, and activators in human bladder cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 13, pp. 3803-13, (2007) (PubMed).

Herlevsen, Theodorescu: "Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76)." in: Biochemical and biophysical research communications, Vol. 362, Issue 1, pp. 56-62, (2007) (PubMed).

Tobias: "What went wrong at Exeter?" in: BMJ (Clinical research ed.), Vol. 297, Issue 6645, pp. 372-3, (1988) (PubMed).

Synonyms and alternative names related to RALBP1

ralA binding protein 1 S homeolog (ralbp1.S), ralA binding protein 1 (RALBP1), ralA binding protein 1 (ralbp1), ralA binding protein 1 (Ralbp1), RALBP1, rip1, Rip1, RIP1, rlip-A, rlip1, RLIP1, rlip76, RLIP76

Protein level used designations for RALBP1

  • ralA binding protein 1
  • Ral interacting protein
  • ralA-binding protein 1
  • ralA-binding protein 1-like
  • DNP-SG ATPase
  • Ral-interacting protein 1
  • dinitrophenyl S-glutathione ATPase
  • cytocentrin
  • ral-interacting protein 1
  • 76 kDa Ral-interacting protein
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