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RAD51 Homolog 产品

(RAD51 Homolog (RAD51))

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The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].

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Recommended RAD51 Homolog 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, IP, WB, ICC
Validations
  • (2)
Cat. No. ABIN7430222
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IP, WB, IF/ICC
Validations
Cat. No. ABIN6336962
Quantity 1 mL
Datasheet Datasheet

Recommended RAD51 Homolog ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959042
Quantity 96 tests
Datasheet Datasheet

Recommended RAD51 Homolog 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386428
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our RAD51 Homolog Products

Sargazi, Saravani, Zavar Reza, Jaliani, Mirinejad, Rezaei, Zarei: "Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid." in: EXCLI journal, Vol. 18, pp. 485-498, (2019) (PubMed).

Synonyms and alternative names related to RAD51 Homolog

RAD51 recombinase (RAD51), BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA

Protein level used designations for RAD51 Homolog

  • BRCA1/BRCA2-containing complex, subunit 5
  • DNA repair protein RAD51 homolog 1
  • RAD51 homolog A
  • RecA, E. coli, homolog of
  • RecA-like protein
  • recombination protein A
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