RAD51 产品
(DNA Repair Protein Homolog 1 (RAD51))
Categories
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].
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Featured RAD51 Categories
RAD51 抗体
High quality antibodies with extensive validation data.
RAD51 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RAD51 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAD51 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (7)
Cat. No.
ABIN519604
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), IP, IF, ICC
Validations
- (4)
- (8)
Cat. No.
ABIN2854762
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
- (2)
- (3)
Cat. No.
ABIN4913431
Quantity
100 μL
Datasheet
Datasheet
Recommended RAD51 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380472
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951284
Quantity
96 tests
Datasheet
Datasheet
Recommended RAD51 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1317281
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3087026
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3121510
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RAD51 Products
: "Genetic determinants of cellular addiction to DNA polymerase theta." in: Nature communications, Vol. 10, Issue 1, pp. 4286, (2020) (PubMed).: "UVB Irradiation Induced Cell Damage and Early Onset of Junbb Expression in Zebrafish." in: Animals : an open access journal from MDPI, Vol. 10, Issue 6, (2020) (PubMed).
: "A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs." in: Cell reports, Vol. 26, Issue 3, pp. 775-787.e5, (2019) (PubMed).
: "Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells." in: eLife, Vol. 8, (2019) (PubMed).
: "Assessing effects of germline exposure to environmental toxicants by high-throughput screening in C. elegans." in: PLoS genetics, Vol. 15, Issue 2, pp. e1007975, (2019) (PubMed).
: "Dibutyl phthalate exposure disrupts the progression of meiotic prophase I by interfering with homologous recombination in fetal mouse oocytes." in: Environmental pollution (Barking, Essex : 1987), Vol. 252, Issue Pt A, pp. 388-398, (2019) (PubMed).
: "BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance." in: Cell reports, Vol. 24, Issue 13, pp. 3513-3527.e7, (2019) (PubMed).
: "Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma." in: Oncotarget, Vol. 9, Issue 4, pp. 4647-4660, (2018) (PubMed).
: "Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling." in: Cell chemical biology, Vol. 25, Issue 6, pp. 677-690.e12, (2018) (PubMed).
: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).
Synonyms and alternative names related to RAD51
RAD51 recombinase (RAD51), RAD51 recombinase (rad51), RAD51 recombinase (Rad51), RAS associated with diabetes protein 51 (RAD51), RAD51 recombinase L homeolog (rad51.L), ATRAD51, AV304093, BRCC5, brcc5, CRAD51, F22D1.20, F22D1_20, HRAD51, HsRad51, HsT16930, MRMV2, rad51, RAD51A, Rad51a, rad51a, RAS associated with diabetes protein 51, RECA, Reca, reca, RGD1563603, wu:fb38e12, xrad51, zgc:77754Protein level used designations for RAD51
- BRCA1/BRCA2-containing complex, subunit 5
- DNA repair protein RAD51 homolog 1
- RAD51 homolog A
- RecA, E. coli, homolog of
- RecA-like protein
- recombination protein A
- RAD51 homolog (RecA homolog, E. coli)
- homolog to S.cerevisiae
- RAD51 homolog
- DNA repair protein RAD51
- DNA repair protein RAD51 homolog A
- RAD51 homolog (RecA homolog)
- XRad51.1
- DNA repair protein RAD51-like 1
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