anti-豚鼠 alpha Actinin 4 抗体 for Immunohistochemistry

Recommended alpha Actinin 4 Antibody

抗原
Actinin, alpha 4 (ACTN4) 抗体
  • fsgs
  • fsgs1
  • C77391
  • ACTININ-4
  • FSGS
  • FSGS1
  • wu:fb53f05
  • zgc:63508
  • actinin alpha 4
  • actinin, alpha 4
  • actinin alpha 4 S homeolog
  • actn4
  • ACTN4
  • Actn4
  • actn4.S
抗原表位
N-Term
15
11
10
5
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
116
46
43
8
5
4
4
3
2
2
1
1
1
1
1
宿主

94
22
克隆类型
多克隆
标记
This alpha Actinin 4 antibody is un-conjugated
5
3
2
2
2
2
2
2
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
96
49
47
20
18
18
10
7
5
4
2
1
1
1
选项

Available images

产品编号 ABIN2775288
$ 229.00
加上运输费 $45.00

General

抗原 Actinin, alpha 4 (ACTN4) 抗体
抗原表位 N-Term
(15), (11), (10), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
(116), (46), (43), (8), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
宿主
(94), (22)
克隆类型
多克隆
标记 This alpha Actinin 4 antibody is un-conjugated
(5), (3), (2), (2), (2), (2), (2), (2), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(96), (49), (47), (20), (18), (18), (10), (7), (5), (4), (2), (1), (1), (1)
Pubmed 3个引用可参考
Supplier

alpha Actinin 4抗体详情

alpha Actinin 4目标详情 使用细节 贮存及处理 References for anti-alpha Actinin 4 antibody (ABIN2775288) 图像
序列 LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM LDAEDIVNTA
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
产品特性 This is a rabbit polyclonal antibody against ACTN4. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human ACTN4
Plasmids, Primers & others

alpha Actinin 4目标详情

alpha Actinin 4抗体详情 使用细节 贮存及处理 References for anti-alpha Actinin 4 antibody (ABIN2775288) 图像 回页首
抗原
别名 ACTN4 (ACTN4 Antibody 摘要)
背景 Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in its gene have been associated with focal and segmental glomerulosclerosis.Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Alias Symbols: DKFZp686K23158, FSGS, FSGS1, ACTININ-4
Protein Interaction Partner: MYOZ2, HUWE1, UBC, BMP7, ACTN3, SUMO2, SUMO3, GNB2, SUMO1, NEDD8, MDM2, HGS, SF3A3, VCP, CDKN2A, ACTN1, PDLIM1, UBD, IGSF8, ICAM1, CD81, SVIL, Fcho2, POT1, VCAM1, TXN, RPS27, MAPK7, KPNA2, ITGA4, FN1, ESR1, CDH1, TRAF3IP1, FMNL1, NOS3, ACTN2, UBASH3B, SHC
Protein Size: 911
分子量 100 kDa
基因ID 81
NCBI登录号 NM_004924, NP_004915
UniProt O43707
途径 Proton Transport

使用细节

alpha Actinin 4抗体详情 alpha Actinin 4目标详情 贮存及处理 References for anti-alpha Actinin 4 antibody (ABIN2775288) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 911 AA

限制 仅限研究用

贮存及处理

alpha Actinin 4抗体详情 alpha Actinin 4目标详情 使用细节 References for anti-alpha Actinin 4 antibody (ABIN2775288) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-alpha Actinin 4 antibody (ABIN2775288)

alpha Actinin 4抗体详情 alpha Actinin 4目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Wei, Gao, Du, Su, Xu: "Angiogenin enhances cell migration by regulating stress fiber assembly and focal adhesion dynamics." in: PLoS ONE, Vol. 6, Issue 12, pp. e28797, 2011

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, 2006

背景

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006

图像

alpha Actinin 4抗体详情 alpha Actinin 4目标详情 使用细节 贮存及处理 References for anti-alpha Actinin 4 antibody (ABIN2775288) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody (ABIN2775288) WB Suggested Anti-ACTN4 Antibody Titration: 0.625ug/ml Positive Control: HCT116 ce...
Western Blotting (WB) image for anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody (ABIN2775288) WB Suggested Anti-ACTN4 Antibody Titration: 0.625 µg/mL Positive Control: HCT116 ce...
Western Blotting (WB) image for anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody (ABIN2775288) Lanes: Lane1: 10 ug ACTN1-GFP transfected COS-7 lysate Lane2: 10 ug ACTN2-GFP trans...
Immunohistochemistry (IHC) image for anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody (ABIN2775288) Sample Type : ACTNX-GFP transfected COS-7 cells Primary Antibody Dilution : 1:1000...