alpha Actinin 4 抗体 (C-Term)
-
- 抗原 See all alpha Actinin 4 (ACTN4) 抗体
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This alpha Actinin 4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
-
Rabbit Polyclonal antibody to alpha Actinin 4 (actinin, alpha 4)
alpha Actinin 4 antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human alpha Actinin 4. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ACTN4 Primary Antibody
-
anti-Actinin, alpha 4 (ACTN4) (AA 592-701) antibody
ACTN4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 1-269) antibodyACTN4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyACTN4 适用: 人 WB, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 160-440) antibodyACTN4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (N-Term) antibodyACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyACTN4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 1-911) antibodyACTN4 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibodyACTN4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 785-813), (C-Term) antibodyACTN4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15705 unconjugated
anti-Actinin, alpha 4 (ACTN4) (C-Term) antibodyACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
-
Positive Control: 293T , A431 , HeLa , HepG2 , A375 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , Mouse brain , PC-12
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.32 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- 抗原
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- 别名
- actinin alpha 4 (ACTN4 产品)
- 别名
- fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
- 背景
-
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Cellular Localization: Nucleus , Cytoplasm - 分子量
- 105 kDa
- 基因ID
- 81
- UniProt
- O43707
- 途径
- Proton Transport
-
