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IFNB1 蛋白

IFNB1 宿主: 人 宿主: CHO Cells Recombinant > 95 % pure Active
产品编号 ABIN935242
发货至: 中国
  • 抗原 See all IFNB1 蛋白
    IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 8
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    资源
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    CHO Cells
    序列
    MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
    产品特性
    Purified recombinant Human IFN beta protein
    Expression System: CHO cells
    Bioactivity: Assay#1: The biological activity of PeproTech's human IFN-gamma was based on analysis using the WISH cell line with VSV as the challenge virus. The specific activitywas determined to be >5 x 10 8 units/mg, Assay#2: Measured by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 20-30 ng/mL.
    纯度
    > 95 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IFNB1 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in water to a concentration of 0.1-1.0 g/mL. Do not vortex. For extended storage, dilute further in a buffer containing a carrier protein (ie: 0.1 % BSA).
    缓冲液
    Lyophilized from 10 mM sodium citrate, with 100 mM NaCl, and 10 mM Sucrose.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
    别名
    IFN beta (IFNB1 产品)
    别名
    IFB Protein, IFF Protein, IFNB Protein, IFN-beta Protein, Ifb Protein, Ifnb Protein, IFNb Protein, interferon beta 1 Protein, interferon beta 1, fibroblast Protein, interferon, beta 1, fibroblast Protein, IFNB1 Protein, Ifnb1 Protein
    背景
    Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNa is an acid stable molecule that signals through IFNa/betaR, which is also used by IFNbeta. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNa contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity.
    Alternative Names: Leukocyte interferon antibody, RMMB1 antibody, Interferon beta antibody, Type I interferon antibody, B cell interferon antibody
    分子量
    20 kDa
    途径
    JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
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