IFNB1 Protein (AA 22-187) (Fc Tag)
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Quick Overview for IFNB1 Protein (AA 22-187) (Fc Tag) (ABIN7092834)
抗原
See all IFNB1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 22-187
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标记
- This IFNB1 protein is labelled with Fc Tag.
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原理
- Recombinant Human IFNB1 with C-terminal human Fc tag
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特异性
- IFNB1(Met22-Asn187) hFc(Glu99-Ala330)
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)
IFNB1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)IFNB1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Interferon, beta 1, Fibroblast (IFNB1) (AA 1-187) protein (GST tag)IFNB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187), (full length) protein (GST tag)IFNB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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别名
- IFNB1
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背景
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IFB,IFF,IFN-beta,IFNB
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015] -
分子量
- predicted molecular mass of 46.2 kDa after removal of the signal peptide. The apparent molecular mass of IFNB1-hFc is 40-55 kDa due to glycosylation.
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UniProt
- P01574
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
抗原
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