IFNB1 Protein (AA 22-182) (His tag)
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北京 101111
Quick Overview for IFNB1 Protein (AA 22-182) (His tag) (ABIN666768)
抗原
See all IFNB1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 22-182
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标记
- This IFNB1 protein is labelled with His tag.
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序列
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INYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN -
产品特性
- Interferon beta 1, 22- 182 aa, Mouse, His-tagged, Recombinant, E.coli
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纯化方法
- > 95% by SDS-PAGE
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内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- 20 mM HEPES buffer ( pH 6.0) containing 0.5M NaCl, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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别名
- IFN-beta 1/IFNB1
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背景
- Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis. Recombinant Interferon beta 1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
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分子量
- 22.0 kDa (182aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_034640
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
抗原
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