IFNB1 Protein (His tag)
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北京 101111
Quick Overview for IFNB1 Protein (His tag) (ABIN7764077)
抗原
See all IFNB1 蛋白蛋白类型
宿主
资源
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标记
- This IFNB1 protein is labelled with His tag.
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原理
- Recombinant Human IFN-beta/IFNB1 Protein
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序列
- MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
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特异性
- Met22-Asn187
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过滤
- 0.22 μm filtered
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内毒素水平
- <0.1EU/mg
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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浓度
- 0.15 mg/mL
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of 25 mM NaAc PH 5.0
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储存条件
- -20 °C,-80 °C
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储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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别名
- IFN-beta/IFNB1
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背景
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Description: Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Large-scale clinical trials have established the clinical efficacy of IFN beta in reducing relapses and slowing disease progression in relapsing-remitting MS. IFN beta therapy was shown to be comparably beneficial for opticospinal MS (OSMS) and conventional MS in Japanese.
Name: IFB, IFF, IFNB, IFN-beta,IFNB1
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基因ID
- 3456
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UniProt
- P01574
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
抗原
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