IFNB1 蛋白
Quick Overview for IFNB1 蛋白 (ABIN934620)
抗原
See all IFNB1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
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Purified recombinant Human IFN beta protein
Expression System: E.coli
Bioactivity: The EC50 for interferon in a cytopathic effect inhibition assay is ~1 U/mL (Human) and ~5 U/mL (Bovine)
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000000 U/mL
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缓冲液
- PBS with 0.1 % BSA, and 11 % glycerol.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -80 °C
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储存方法
- Aliquot and store at -70 °C or lower.
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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别名
- IFN beta
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背景
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Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. The IFN-beta proteins are produced in large quantities by fibroblasts. They have antiviral activity which is mainly involved in innate immune response. Two types of IFN-beta have been described, IFN-beta1 (IFNB1) and IFN-beta3 (IFNB3).
Alternative Names: RMMB1 protein, B cell interferon protein, Leukocyte interferon protein, Type I interferon protein, Interferon beta protein -
分子量
- 20 kDa
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
抗原
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