TNF alpha 蛋白
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北京 101111
Quick Overview for TNF alpha 蛋白 (ABIN7937241)
抗原
See all TNF alpha 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2, Variant
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序列
- MRKRKPVAHV VANPQAEGQL QWLNRRANAL LANGVELRDN QLVVPSEGLY LIYSQVLFKG QGCPSTHVLL THTISRIAVS YQTKVNLLSA IKSPCQRETP EGAEAKPWYE PIYLGGVFQL EKGDRLSAEI NRPDYLDFAE SGQVYFGIIA F
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 1 EU/ug of rHu TNF-alpha/TNFSF2, Variant as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.01 ng/ml, corresponding to a specific activity of > 1.0 x107 IU/mg in the presence of actinomycin D.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.0.
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- Tumor Necrosis Factor-alpha
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基因ID
- 7124
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UniProt
- P01375
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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