TNF alpha Protein (AA 80-235)
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北京 101111
Quick Overview for TNF alpha Protein (AA 80-235) (ABIN7678814)
抗原
See all TNF alpha 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 80-235
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原理
- Recombinant Mouse TNFa/TNF-alpha Protein, No tag (Active)
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内毒素水平
- <1 EU/μg of the protein by the LAL method.
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Biological Activity Comment
- Recombinant Mouse TNFa/TNF-alpha (ABIN7607268 and ABIN7678814) induces cytotoxicity in the mouse fibroblast cells (L-929) in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 29-116 pg/mL, corresponding to a specific activity of 8.62x10^6-3.45x10^7 units/mg.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
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有效期
- 12 months
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- Tumor necrosis factor
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背景
- Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor, membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, TNF, TNFA, TNFSF2
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UniProt
- P06804
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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