Vitronectin Protein (VTN) (His tag)
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- 抗原 See all Vitronectin (VTN) 蛋白
- Vitronectin (VTN)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Vitronectin protein is labelled with His tag.
- 原理
- Recombinant Human Vitronectin/V75/VTN Protein
- 序列
- DQESCKGRCT EGFNVDKKCQ CDELCSYYQS CCTDYTAECK PQVTRGDVFT MPEDEYTVYD DGEEKNNATV HEQVGGPSLT SDLQAQSKGN PEQTPVLKPE EEAPAPEVGA SKPEGIDSRP ETLHPGRPQP PAEEELCSGK PFDAFTDLKN GSLFAFRGQY CYELDEKAVR PGYPKLIRDV WGIEGPIDAA FTRINCQGKT YLFKGSQYWR FEDGVLDPDY PRNISDGFDG IPDNVDAALA LPAHSYSGRE RVYFFKGKQY WEYQFQHQPS QEECEGSSLS AVFEHFAMMQ RDSWEDIFEL LFWGRTSAGT RQPQFISRDW HGVPGQVDAA MAGRIYISGM APRPSLAKKQ RFRHRNRKGY RSQRGHSRGR NQNSRRPSRA TWLSLFSSEE SNLGANNYDD YRMDWLVPAT CEPIQSVFFF SGDKYYRVNL RTRRVDTVDP PYPRSIAQYW LGCPAPGHL
- 特异性
- Asp20-Leu478
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <1EU/μg
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of B16-F1 mouse melanoma cells. When 5x104 cells/well are added to Vitronectin coated plates (5 μg/mL with 100 μL/well), approximately >85% will adhere after 30 minutes at 37 °C.
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- Discover our top product VTN 蛋白
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Vitronectin (VTN) (Active) protein (His tag)
VTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
Vitronectin (VTN) (AA 1-478) protein (GST tag)VTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vitronectin (VTN) (AA 20-398) protein (His tag)Crystallography grade VTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Vitronectin (VTN) (AA 399-478) protein (His tag)Crystallography grade VTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Vitronectin (VTN) (AA 20-478) protein (His tag)Crystallography grade VTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- Vitronectin (VTN)
- 别名
- Vitronectin/V75/VTN (VTN 产品)
- 别名
- VTN Protein, DKFZp470F0511 Protein, LOC100228142 Protein, vtn Protein, zgc:112277 Protein, V75 Protein, VN Protein, VNT Protein, AI256434 Protein, Vn Protein, Aa1018 Protein, vitronectin Protein, vitronectin a Protein, vitronectin b Protein, vitronectin L homeolog Protein, VTN Protein, vtn Protein, vtna Protein, vtnb Protein, CpipJ_CPIJ016691 Protein, vtn.L Protein, Vtn Protein
- 背景
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Description: Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.
Name: V75, VN, VNT,VTN,VN,VNT
- 基因ID
- 7448
- UniProt
- P04004
- 途径
- Autophagy, Smooth Muscle Cell Migration
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