Vitronectin Protein (VTN) (His tag)
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- 抗原 See all Vitronectin (VTN) 蛋白
- Vitronectin (VTN)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This Vitronectin protein is labelled with His tag.
- 原理
- Recombinant Mouse Vitronectin/VTN Protein (His Tag)(Active)
- 序列
- Met 1-Lys 478
- 产品特性
- A DNA sequence encoding the mouse vitronectin (NP_035837.1) (Met 1-Lys 478) was expressed, with a polyhistidine tag at the C-terminus.
- 纯度
- > 94 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of DU145 human prostate carcinoma cells.When cells are added to mouse Vitronectin coated plates (10 μg/mL and 100 μL/well), > 60% cells will adhere specifically after 30 minutes at 37 °C.
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Vitronectin (VTN) (AA 1-478) protein (GST tag)
VTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vitronectin (VTN) (AA 20-398) protein (His tag)Crystallography grade VTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Vitronectin (VTN) (AA 399-478) protein (His tag)Crystallography grade VTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Vitronectin (VTN) (AA 20-478) protein (His tag)Crystallography grade VTN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Vitronectin (VTN)
- 别名
- Vitronectin/VTN (VTN 产品)
- 别名
- VTN Protein, DKFZp470F0511 Protein, LOC100228142 Protein, vtn Protein, zgc:112277 Protein, V75 Protein, VN Protein, VNT Protein, AI256434 Protein, Vn Protein, Aa1018 Protein, vitronectin Protein, vitronectin a Protein, vitronectin b Protein, vitronectin L homeolog Protein, VTN Protein, vtn Protein, vtna Protein, vtnb Protein, CpipJ_CPIJ016691 Protein, vtn.L Protein, Vtn Protein
- 背景
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Background: Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.
Synonym: AI256434,Vn
- 分子量
- 54.2 kDa
- NCBI登录号
- NP_035837
- 途径
- Autophagy, Smooth Muscle Cell Migration
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