VEGFC Protein (His tag)
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- 抗原 See all VEGFC 蛋白
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- 蛋白类型
- Recombinant
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宿主
- 大鼠, 小鼠
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资源
- HEK-293 Cells
- 标记
- This VEGFC protein is labelled with His tag.
- 原理
- Recombinant Mouse/Rat VEGF-C Protein
- 序列
- AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGAATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTGYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
- 特异性
- Ala108-Arg223
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <1EU/μg
- Top Product
- Discover our top product VEGFC 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 浓度
- 0.58 mg/mL
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, 10 % glycerol, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- 别名
- VEGF-C (VEGFC 产品)
- 别名
- VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein
- 背景
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Description: Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGFR-3 axis, through different signaling pathways, plays a critical role in cancer progression by regulating different cellular functions, such as invasion, proliferation, and resistance to chemotherapy. Thus, targeting the VEGF-C/VEGFR-3 axis may be therapeutically significant for certain types of tumors.
Name: VEGFC,Flt4-L,LMPH1D,VRP
- 基因ID
- 22341
- UniProt
- P97953
- 途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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