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VEGFC Protein (His tag)

VEGFC 宿主: 大鼠, 小鼠 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7536561
发货至: 中国
  • 抗原 See all VEGFC 蛋白
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    蛋白类型
    Recombinant
    宿主
    • 16
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠
    资源
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This VEGFC protein is labelled with His tag.
    原理
    Recombinant Mouse/Rat VEGF-C Protein
    序列
    AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGAATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTGYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
    特异性
    Ala108-Arg223
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <1EU/μg
    Top Product
    Discover our top product VEGFC 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    浓度
    0.58 mg/mL
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, 10 % glycerol, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    别名
    VEGF-C (VEGFC 产品)
    别名
    VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein
    背景

    Description: Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGFR-3 axis, through different signaling pathways, plays a critical role in cancer progression by regulating different cellular functions, such as invasion, proliferation, and resistance to chemotherapy. Thus, targeting the VEGF-C/VEGFR-3 axis may be therapeutically significant for certain types of tumors.

    Name: VEGFC,Flt4-L,LMPH1D,VRP

    基因ID
    22341
    UniProt
    P97953
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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