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VEGFC Protein (AA 103-227) (His tag)

VEGFC 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181912
发货至: 中国
  • 抗原 See all VEGFC 蛋白
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    蛋白类型
    Recombinant
    产品特性
    AA 103-227
    宿主
    • 15
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    资源
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This VEGFC protein is labelled with His tag.
    序列
    AA 103-227
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15 kDa. The protein migrates as 18-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product VEGFC 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
  • de Guzman, Rabbany: "PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery." in: Journal of drug delivery, Vol. 2016, pp. 7843951, (2016) (PubMed).

  • 抗原
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    别名
    VEGF-C (VEGFC 产品)
    别名
    VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein
    背景
    Vascular endothelial growth factor C is also known as VEGFC, Flt4-L and VRP, it contains the C-terminal propeptide which has an unusual structure with tandemly repeated cysteine-rich motifs. Upon biosynthesis, VEGFC is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGFC is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. The structure and function of this protein is similar to those of vascular endothelial growth factor D (VEGF-D). VEGFC may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Overexpression of VEGF-C causes lymphatics to enlarge possibly facilitates metastasis.
    分子量
    14.9 kDa
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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