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IL18BP Protein (Fc Tag,His tag)

IL18BP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7534133
发货至: 中国
  • 抗原 See all IL18BP 蛋白
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 12
    • 6
    • 3
    • 2
    • 1
    资源
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL18BP protein is labelled with Fc Tag,His tag.
    原理
    Active Recombinant Human IL-18BP Protein
    序列
    TPVSQTTTAA TASVRSTKDP CPSQPPVFPA AKQCPALEVT WPEVEVPLNG TLSLSCVACS RFPNFSILYW LGNGSFIEHL PGRLWEGSTS RERGSTGTQL CKALVLEQLT PALHSTNFSC VLVDPEQVVQ RHVVLAQLWA GLRATLPPTQ EALPSSHSSP QQQG
    特异性
    Thr31-Gly194
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human IL18BP at 2 μg/mL (100 μL/well) can bind IL18 with a linear range of 0.128-47.02 ng/mL.
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    Discover our top product IL18BP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    别名
    IL-18BP (IL18BP 产品)
    别名
    IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
    背景

    Description: Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease.

    Name: IL18BP,IL18BPa

    基因ID
    10068
    UniProt
    O95998
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