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IL18BP Protein (AA 29-193) (His tag)

IL18BP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274981
发货至: 中国
  • 抗原 See all IL18BP 蛋白
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    蛋白类型
    Recombinant
    产品特性
    AA 29-193
    宿主
    • 13
    • 5
    • 3
    • 2
    • 1
    小鼠
    资源
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL18BP protein is labelled with His tag.
    原理
    Mouse IL-18BP Protein
    序列
    Thr29-Ala193
    产品特性
    Recombinant Mouse IL-18BP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr29-Ala193.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product IL18BP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    别名
    IL-18BP (IL18BP 产品)
    别名
    IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
    背景
    Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
    分子量
    19.1 kDa. Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9Z0M9
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