IL18BP Protein (AA 31-194) (His tag)
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- 抗原 See all IL18BP 蛋白
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-194
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL18BP protein is labelled with His tag.
- 原理
- Human IL-18BP Protein
- 序列
- Thr31-Gly194
- 产品特性
- Recombinant Human IL-18BP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr31-Gly194.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.26nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL18BP 蛋白
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Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (Fc Tag)
IL18BP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His-Avi Tag,Biotin)IL18BP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (His tag)IL18BP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (Fc Tag)IL18BP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (GST tag)IL18BP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His tag)Crystallography grade IL18BP 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (His tag)Crystallography grade IL18BP 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- 别名
- IL-18BP (IL18BP 产品)
- 别名
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- 背景
- Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
- 分子量
- 18.7 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result.
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