FZD4 Protein (Fc Tag,His tag)
-
- 抗原 See all FZD4 蛋白
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This FZD4 protein is labelled with Fc Tag,His tag.
- 原理
- Recombinant Human Frizzled-4/FZD4/CD344 Protein
- 序列
- FGDEEERRCD PIRISMCQNL GYNVTKMPNL VGHELQTDAE LQLTTFTPLI QYGCSSQLQF FLCSVYVPMC TEKINIPIGP CGGMCLSVKR RCEPVLKEFG FAWPESLNCS KFPPQNDHNH MCMEGPGDEE VPLPHKTPIQ PGEE
- 特异性
- Phe37-Glu180
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.1EU/μg
- Top Product
- Discover our top product FZD4 蛋白
-
Frizzled Family Receptor 4 (FZD4) protein (His tag)
FZD4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Frizzled Family Receptor 4 (FZD4) (AA 107-206) protein (GST tag)FZD4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Frizzled Family Receptor 4 (FZD4) (AA 1-537) protein (GST tag)FZD4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Frizzled Family Receptor 4 (FZD4) (AA 37-222) protein (His tag)Crystallography grade FZD4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Frizzled Family Receptor 4 (FZD4) (AA 37-222) protein (His tag)Crystallography grade FZD4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Frizzled Family Receptor 4 (FZD4) (AA 37-537) protein (rho-1D4 tag)Crystallography grade FZD4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Frizzled Family Receptor 4 (FZD4) (AA 37-537) protein (rho-1D4 tag)Crystallography grade FZD4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
- 抗原
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- 别名
- Frizzled-4/FZD4/CD344 (FZD4 产品)
- 别名
- CG4626 Protein, DFz4 Protein, Dfz4 Protein, Dm Fz4 Protein, Dmel\\CG4626 Protein, Fz4 Protein, anon-WO0170980.10 Protein, anon-WO0170980.11 Protein, fz1 Protein, zg01 Protein, CD344 Protein, EVR1 Protein, FEVR Protein, FZD4S Protein, Fz-4 Protein, FzE4 Protein, GPCR Protein, hFz4 Protein, frizzled4 Protein, fz4 Protein, FZ-4 Protein, frizzled 4 Protein, frizzled class receptor 4 Protein, frizzled-4 Protein, frizzled class receptor 4 S homeolog Protein, fz4 Protein, fzd4 Protein, Tsp_10376 Protein, FZD4 Protein, Fzd4 Protein, fzd4.S Protein
- 背景
-
Description: Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR.
Name: FZD4,CD344,EVR1,FEVR,FZD4S,Fz-4,Fz4,FzE4,GPCR,hFz4
- 基因ID
- 8322
- UniProt
- Q9ULV1
- 途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
-
