FZD1 Protein (Fc Tag,His tag)
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- 抗原 See all FZD1 (Fzd1) 蛋白
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FZD1 protein is labelled with Fc Tag,His tag.
- 原理
- Recombinant Human Frizzled-1/FZD1 Protein
- 序列
- QAAGQGPGQG PGPGQQPPPP PQQQQSGQQY NGERGISVPD HGYCQPISIP LCTDIAYNQT IMPNLLGHTN QEDAGLEVHQ FYPLVKVQCS AELKFFLCSM YAPVCTVLEQ ALPPCRSLCE RARQGCEALM NKFGFQWPDT LKCEKFPVHG AGELCVGQNT SDKGTPTPSL LPEFWTSNPQ H
- 特异性
- Gln73-His253
- 纯度
- > 92 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product Fzd1 蛋白
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Frizzled Family Receptor 1 (Fzd1) protein (Fc Tag)
Fzd1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Frizzled Family Receptor 1 (Fzd1) protein (His tag)Fzd1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- 抗原
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- 别名
- Frizzled-1/FZD1 (Fzd1 产品)
- 别名
- CG17697 Protein, CG3646 Protein, DFZ1 Protein, DFz Protein, DFz1 Protein, Dfz1 Protein, Dm Fz1 Protein, Dmel\\CG17697 Protein, FZ Protein, Frz Protein, Fz Protein, Fz1 Protein, frz Protein, fz1 Protein, fz[[1]] Protein, Fz-1 Protein, cFz-1 Protein, Xfrizzled-1 Protein, frizzled1 Protein, frz-1 Protein, frz1 Protein, fzd1-A Protein, AW227548 Protein, FZ-1 Protein, frizzled Protein, frizzled class receptor 1 Protein, frizzled class receptor 1 L homeolog Protein, fz Protein, FZD1 Protein, Fzd1 Protein, fzd1.L Protein
- 背景
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Description: This protein belongs to the G-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol. Frizzled proteins and the genes encoding them have been identified in an array of animals, from sponges to humans. Frizzled proteins play key roles in governing cell polarity, embryonic development, formation of neural synapses, cell proliferation, and many other processes in developing and adult organisms. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.
Name: FZD1
- 基因ID
- 8321
- UniProt
- Q9UP38
- 途径
- WNT signaling, Asymmetric Protein Localization
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