DDR2 Protein (His tag)
-
- 抗原 See all DDR2 蛋白
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This DDR2 protein is labelled with His tag.
- 原理
- Active Recombinant Human DDR2/CD167b Protein
- 序列
- QVNPAICRYP LGMSGGQIPD EDITASSQWS ESTAAKYGRL DSEEGDGAWC PEIPVEPDDL KEFLQIDLHT LHFITLVGTQ GRHAGGHGIE FAPMYKINYS RDGTRWISWR NRHGKQVLDG NSNPYDIFLK DLEPPIVARF VRFIPVTDHS MNVCMRVELY GCVWLDGLVS YNAPAGQQFV LPGGSIIYLN DSVYDGAVGY SMTEGLGQLT DGVSGLDDFT QTHEYHVWPG YDYVGWRNES ATNGYIEIMF EFDRIRNFTT MKVHCNNMFA KGVKIFKEVQ CYFRSEASEW EPNAISFPLV LDDVNPSARF VTVPLHHRMA SAIKCQYHFA DTWMMFSEIT FQSDAAMYNN SEALPTSPMA PTTYDPMLKV DDSNTR
- 特异性
- Gln24-Arg399
- 纯度
- > 97 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human DDR2 Protein at 1 μg/mL (100 μL/well) can bind DDR2 Rabbit mAb with a linear range of 0.486-33.97 ng/mL.
- Top Product
- Discover our top product DDR2 蛋白
-
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 22-399) protein (His tag)
DDR2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 22-399) protein (His tag)DDR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) protein (His tag)DDR2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 1-855) protein (GST tag)DDR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 277-377) protein (GST tag)DDR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Active) protein (GST tag,His tag)DDR2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Active) protein (His tag)DDR2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Active) protein (Fc Tag)DDR2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
-
Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
-
- 抗原
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- 别名
- DDR2/CD167b (DDR2 产品)
- 别名
- MIG20a Protein, NTRKR3 Protein, TKT Protein, TYRO10 Protein, AW495251 Protein, Ntrkr3 Protein, tyro10 Protein, DDR2 Protein, Tyro10 Protein, ddr2 Protein, si:ch211-193c2.1 Protein, discoidin domain receptor tyrosine kinase 2 Protein, discoidin domain receptor family, member 2 Protein, discoidin domain receptor family, member 2, like Protein, DDR2 Protein, Ddr2 Protein, ddr2l Protein
- 背景
-
Description: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Name: DDR2,MIG20a,NTRKR3,TKT,TYRO10, NTRKR3, TKT, TYRO10
- 基因ID
- 4921
- UniProt
- Q16832
- 途径
- RTK signaling
-
