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CA9 Protein (His tag)

CA9 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7535681
发货至: 中国
  • 抗原 See all CA9 蛋白
    CA9 (Carbonic Anhydrase IX (CA9))
    蛋白类型
    Recombinant
    宿主
    • 21
    • 6
    • 2
    • 2
    小鼠
    资源
    • 19
    • 6
    • 4
    • 1
    • 1
    HEK-293 Cells
    标记
    This CA9 protein is labelled with His tag.
    原理
    Active Recombinant Mouse Carbonic Anhydrase IX/CA9 Protein
    序列
    QPQGLSGMQG EPSLGDSSSG EDELGVDVLP SEEDAPEEAD PPDGEDPPEV NSEDRMEESL GLEDLSTPEA PEHSQGSHGD EKGGGHSHWS YGGTLLWPQV SPACAGRFQS PVDIRLERTA FCRTLQPLEL LGYELQPLPE LSLSNNGHTV QLTLPPGLKM ALGPGQEYRA LQLHLHWGTS DHPGSEHTVN GHRFPAEIHV VHLSTAFSEL HEALGRPGGL AVLAAFLQES PEENSAYEQL LSHLEEISEE GSKIEIPGLD VSALLPSDLS RYYRYEGSLT TPPCSQGVIW TVFNETVKLS AKQLHTLSVS LWGPRDSRLQ LNFRATQPLN GRTIEASFPA AEDSSPEPVH VNSCFTAGD
    特异性
    Gln32-Asp390
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product CA9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    CA9 (Carbonic Anhydrase IX (CA9))
    别名
    Carbonic Anhydrase IX/CA9 (CA9 产品)
    别名
    CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
    背景

    Description: Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3-) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.

    Name: CAIX,CA9,CA-IX,G250,MN,P54,58N,pMW1,CA9

    基因ID
    230099
    UniProt
    Q8VHB5
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