电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CA9 Protein (His tag)

CA9 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
产品编号 ABIN7194573
发货至: 中国
  • 抗原 See all CA9 蛋白
    CA9 (Carbonic Anhydrase IX (CA9))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 21
    • 6
    • 2
    • 2
    小鼠
    资源
    • 19
    • 6
    • 4
    • 1
    • 1
    HEK-293 Cells
    标记
    This CA9 protein is labelled with His tag.
    原理
    Recombinant Mouse Carbonic Anhydrase IX/CA9 Protein (His Tag)(Active)
    序列
    Met 1-Asp 390
    产品特性
    A DNA sequence encoding the extracellular domain of mouse CAR9 (NP_647466.2) (Met 1-Asp 390) was expressed, with a C-terminal polyhistidine tag.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its esterase activity. The specific activity is >100 pmoles/min/μg.
    Top Product
    Discover our top product CA9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CA9 (Carbonic Anhydrase IX (CA9))
    别名
    Carbonic Anhydrase IX/CA9 (CA9 产品)
    别名
    CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
    背景

    Background: Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: RP23-195K8.9, CAIX, Ca9, MN/CA9

    分子量
    40.3 kDa
    NCBI登录号
    NP_647466
You are here: