VEGF121 Protein (AA 1-147) (His tag)
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- 抗原 See all VEGF121 蛋白
- VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-147
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This VEGF121 protein is labelled with His tag.
- 序列
- Met1-Arg147
- 产品特性
- A DNA sequence encoding theHuman VEGF121 protein (P15692-9) (Met1-Arg147) was expressed with a C-His.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product VEGF121 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))
- 别名
- VEGF121 (VEGF121 产品)
- 背景
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Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform ', ' binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.
Synonym: VEGF-A,Vascular permeability factor,VPF,VEGFA
- 分子量
- 17.2 kDa
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