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VEGF121 Protein (AA 1-147) (His tag)

VEGF121 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505598
发货至: 中国
  • 抗原 See all VEGF121 蛋白
    VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))
    蛋白类型
    Recombinant
    产品特性
    AA 1-147
    宿主
    • 14
    • 1
    • 1
    资源
    • 10
    • 5
    • 1
    HEK-293 Cells
    标记
    This VEGF121 protein is labelled with His tag.
    序列
    Met1-Arg147
    产品特性
    A DNA sequence encoding theHuman VEGF121 protein (P15692-9) (Met1-Arg147) was expressed with a C-His.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product VEGF121 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))
    别名
    VEGF121 (VEGF121 产品)
    背景

    Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform ', ' binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.

    Synonym: VEGF-A,Vascular permeability factor,VPF,VEGFA

    分子量
    17.2 kDa
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