HIF1A Protein (AA 576-785)
-
- 抗原 See all HIF1A 蛋白
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 576-785
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 序列
- Ser 576-Gln785
- 产品特性
- A DNA sequence encoding the Human HIF1A Protein(Q16665-1)(576-785)was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product HIF1A 蛋白
-
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 1-735) protein (GST tag)
HIF1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 576-785) protein (His tag)HIF1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 575-825) protein (His tag)HIF1A 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 574-799) protein (His tag)HIF1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 717-826) protein (GST tag)HIF1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 1-85) protein (His tag)HIF1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS – PAGE SDS
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 1-826) protein (Strep Tag)Crystallography grade HIF1A 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 1-836) protein (Strep Tag)Crystallography grade HIF1A 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
-
- 抗原
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- 别名
- HIF1A (HIF1A 产品)
- 别名
- hif1a Protein, AA959795 Protein, HIF1alpha Protein, MOP1 Protein, bHLHe78 Protein, HIF-1A Protein, HIF-1alpha Protein, HIF1 Protein, HIF1-ALPHA Protein, PASD8 Protein, HIF1-alpha Protein, hif-1a Protein, hypoxia inducible factor 1 alpha Protein, hypoxia inducible factor 1, alpha subunit Protein, hypoxia inducible factor 1 alpha subunit Protein, HIF (Hypoxia Inducible Factor) homologa Protein, hif-1a Protein, Hif1a Protein, HIF1A Protein, hif1a Protein, hif-1 Protein
- 背景
-
Background: Functions as a master transcriptional regulator of the adaptive response to hypoxia.Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.Heterodimerizes with ARNT, heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters.
Synonym: Hypoxia-inducible factor 1-alpha,HIF-1-alpha,HIF1-alpha,ARNT-interacting protein,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,bHLHe78,Member of PAS protein 1,PAS domain-containing protein 8,BHLHE78, MOP1,PASD8
- 分子量
- 25.2 kDa
- UniProt
- Q16665
- 途径
- Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, Warburg Effect
-
