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HIF1A 产品

(Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))

Categories

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].

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Featured HIF1A Categories

HIF1A 抗体

High quality antibodies with extensive validation data.

HIF1A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HIF1A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HIF1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (10)
  • (7)
Cat. No. ABIN672546
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (33)
  • (5)
Cat. No. ABIN3043841
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7439318
Quantity 100 μL
Datasheet Datasheet

Recommended HIF1A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (6)
Cat. No. ABIN6574209
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6956645
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (1)
Cat. No. ABIN6956647
Quantity 96 tests
Datasheet Datasheet

Recommended HIF1A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (3)
  • (1)
Cat. No. ABIN1306618
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667163
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123398
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our HIF1A Products

Mahiddine, Blaisdell, Ma, Créquer-Grandhomme, Lowell, Erlebacher: "Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils." in: The Journal of clinical investigation, Vol. 130, Issue 1, pp. 389-403, (2020) (PubMed).

Di Gioia, Spreafico, Springstead, Mendelson, Joehanes, Levy, Zanoni: "Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation." in: Nature immunology, Vol. 21, Issue 1, pp. 42-53, (2020) (PubMed).

Ferreira, Rosa Soares, Ramalho, Ribeiro-Rodrigues, Máximo, Zuzarte, Girão, Pereira: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).

Cheng, Liu, Tan, Sun, Guan, Jiang, Yang, Kuang: "Integrated serum metabolomics and network pharmacology approach to reveal the potential mechanisms of withanolides from the leaves of Datura metel L. on psoriasis." in: Journal of pharmaceutical and biomedical analysis, Vol. 186, pp. 113277, (2020) (PubMed).

Ding, Gong, Yang, Zou, Liu, Zhang, Li: "Lactobacillus rhamnosus GG Ameliorates Liver Injury and Hypoxic Hepatitis in Rat Model of CLP-Induced Sepsis." in: Digestive diseases and sciences, Vol. 64, Issue 10, pp. 2867-2877, (2020) (PubMed).

Fu, Wang, Xu, Chen, Li, Liao, Ma, Jiang, Xu, Xu, Shen, Song, Gao, Han, Zhang: "HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury." in: Redox biology, Vol. 36, pp. 101671, (2020) (PubMed).

Chen, Deng, Gan, Li, Huang, Lu, Wei, Su, Luo, Zou, Hong, Cao, Liu, Chi: "NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma." in: Molecular neurodegeneration, Vol. 15, Issue 1, pp. 26, (2020) (PubMed).

Tayman, Kurgan, Önder, Güney, Serdar, Kantarcı, Günhan et al.: "A disintegrin-like and metalloproteinase with thrombospondin-1 (ADAMTS-1) levels in gingival crevicular fluid correlate with vascular endothelial growth factor-A, hypoxia-inducible factor-1α, and ..." in: Journal of periodontology, Vol. 90, Issue 10, pp. 1182-1189, (2020) (PubMed).

Zhao, Zhou, Xu, Xu, Xu, Ping, Liu, Zhou, Wang, Jia: "Hypoxia-Preconditioned Adipose-Derived Endothelial Progenitor Cells Promote Bladder Augmentation." in: Tissue engineering. Part A, Vol. 26, Issue 1-2, pp. 78-92, (2020) (PubMed).

Kasture, Sundrani, Dalvi, Swamy, Kale, Joshi: "Maternal omega-3 fatty acids and vitamin E improve placental angiogenesis in late-onset but not early-onset preeclampsia." in: Molecular and cellular biochemistry, Vol. 461, Issue 1-2, pp. 159-170, (2020) (PubMed).

Synonyms and alternative names related to HIF1A

hypoxia inducible factor 1 alpha (hif-1a), hypoxia inducible factor 1, alpha subunit (Hif1a), hypoxia inducible factor 1 alpha subunit (HIF1A), hypoxia inducible factor 1 alpha subunit (Hif1a), hypoxia inducible factor 1 alpha subunit (hif1a), HIF (Hypoxia Inducible Factor) homologa (hif-1), AA959795, bHLHe78, HIF-1A, hif-1a, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1-alpha, hif1a, HIF1alpha, MOP1, PASD8

Protein level used designations for HIF1A

  • HIF-1 alpha
  • HIF-1-alpha
  • HIF1 alpha
  • HIF1-alpha
  • Hypoxia-inducible factor 1 alpha
  • hypoxia-inducible factor 1-alpha
  • ARNT-interacting protein
  • ARNT interacting protein
  • PAS domain-containing protein 8
  • basic-helix-loop-helix-PAS protein MOP1
  • class E basic helix-loop-helix protein 78
  • hypoxia-inducible factor 1 alpha isoform I.3
  • hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • hypoxia-inducible factor1alpha
  • member of PAS protein 1
  • member of PAS superfamily 1
  • hypoxia-inducible factor 1 alpha
  • hypoxia inducible factor 1 alpha subunit
  • hypoxia inducible factor 1, alpha subunit
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