电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

HIF1AN 产品

(Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Categories

  • HIF1AN 抗体
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured HIF1AN Categories

HIF1AN 抗体

High quality antibodies with extensive validation data.

Recommended HIF1AN 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7441979
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP, IF
Validations
  • (6)
Cat. No. ABIN527607
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, IF
Validations
  • (5)
Cat. No. ABIN7156025
Quantity 100 μg
Datasheet Datasheet

Recommended HIF1AN ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956649
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1137714
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN454393
Quantity 96 tests
Datasheet Datasheet

Recommended HIF1AN 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306622
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3092929
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3136220
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HIF1AN Products

Pillai, Mihi, Ishiwata, Nakamura, Sakuragi, Finkelstein, McGargill, Nakayama, Ayabe, Coleman, Bix: "Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211244, (2019) (PubMed).

Pickel, Günter, Ruiz-Serrano, Spielmann, Fabrizio, Wolski, Peet, Wenger, Scholz: "Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1." in: Redox biology, Vol. 26, pp. 101265, (2019) (PubMed).

Bullen, Tchernyshyov, Holewinski, DeVine, Wu, Venkatraman, Kass, Cole, Van Eyk, Semenza: "Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1." in: Science signaling, Vol. 9, Issue 430, pp. ra56, (2017) (PubMed).

Huang, Zhao, Wang, Gao, Liang, An, Bai, Chen, Han, Qin: "miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages." in: Frontiers in immunology, Vol. 8, pp. 1327, (2017) (PubMed).

Nakaoka, Hara, Yoshino, Kanamori, Matsui, Shimamura, Sato, Murakami, Seiki, Sakamoto: "NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells." in: Scientific reports, Vol. 6, pp. 22784, (2016) (PubMed).

Mysore, Szablowski, Dervan, Frost: "A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity." in: Molecular cancer research : MCR, Vol. 14, Issue 3, pp. 253-66, (2016) (PubMed).

Karttunen, Duffield, Scrimgeour, Squires, Lim, Dallas, Scragg, Chicher, Dave, Whitelaw, Peers, Gorman, Gleadle, Rychkov, Peet: "Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel." in: Journal of cell science, Vol. 128, Issue 2, pp. 225-31, (2015) (PubMed).

Kiriakidis, Henze, Kruszynska-Ziaja, Skobridis, Theodorou, Paleolog, Mazzone: "Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 7, pp. 2814-27, (2015) (PubMed).

Rawluszko, Bujnicka, Horbacka, Krokowicz, Jagodziński: "Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer." in: BMC cancer, Vol. 13, pp. 526, (2014) (PubMed).

Janke, Brockmeier, Kuhlmann, Eisenacher, Nolde, Meyer, Mairbäurl, Metzen: "Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2)." in: Journal of cell science, Vol. 126, Issue Pt 12, pp. 2629-40, (2013) (PubMed).

Synonyms and alternative names related to HIF1AN

hypoxia inducible factor 1 alpha subunit inhibitor (HIF1AN), hypoxia-inducible factor 1, alpha subunit inhibitor (Hif1an), hypoxia inducible factor 1, alpha subunit inhibitor (hif1an), hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog (hif1an.S), hypoxia inducible factor 1 alpha subunit inhibitor (Hif1an), 2310046M24Rik, A830014H24Rik, cb728, FIH1, id:ibd5139

Protein level used designations for HIF1AN

  • FIH-1
  • factor inhibiting HIF-1
  • factor inhibiting HIF1
  • hypoxia-inducible factor 1-alpha inhibitor
  • hypoxia-inducible factor asparagine hydroxylase
  • peptide-aspartate beta-dioxygenase
  • hypoxia-inducible factor 1, alpha subunit inhibitor
  • LOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor
You are here:
客服