EGFRviii Protein (APC,His tag)
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- 抗原 See all EGFRviii (EGFRv3) products
- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EGFRviii protein is labelled with APC,His tag.
- 原理
- APC-Labeled Human EGFRvIII Protein, His TagStar Staining
- 序列
- Leu 25 - Ser 378
- 产品特性
- APC-Labeled Human EGFRvIII, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 378 (Accession # NP_001333870.1).
- 纯度
- 90 %
- 内毒素水平
- 1.0 EU per μg
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EGFR vIII (EGFRv3) (AA 25-378) protein (His-Avi Tag,Biotin)
EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EGFR vIII (EGFRv3) protein (His-Avi Tag)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
EGFR vIII (EGFRv3) (AA 25-378) protein (FITC,His-Avi Tag)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
EGFR vIII (EGFRv3) (AA 25-378) protein (PE,His-Avi Tag)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant
EGFR vIII (EGFRv3) (AA 25-378) (Active) protein (His tag,FITC)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 说明
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This protein carries a polyhistidine tag at the C-terminus. (APC ,10xHis) The protein has a calculated MW of 53.0 kDa.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, 0.2 % BSA, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C, avoid light
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- 抗原
- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
- 别名
- EGFRvIII (EGFRv3 产品)
- 背景
- The epidermal growth factor receptor (EGFR, ErbB-1, HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. The type III EGF deletion mutant receptor (EGFRvIII) is the most common mutation and was first identified in primary human glioblastoma tumors. This tumor-specific antigen is ligand-independent, contains a constitutively active tyrosine kinase domain, and has been shown to be present in a number of human malignancies. EGFRvIII has been selected as a target for CAR-modified T-cell studies in recent years.
- 分子量
- 53.0 kDa
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