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EGFRviii Protein (AA 25-378) (FITC,His-Avi Tag)

EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7274519
发货至: 中国
  • 抗原 See all EGFRviii (EGFRv3) products
    EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
    蛋白类型
    Recombinant
    产品特性
    AA 25-378
    宿主
    资源
    • 8
    HEK-293 Cells
    标记
    This EGFRviii protein is labelled with FITC,His-Avi Tag.
    原理
    FITC-Labeled Human EGFRVIII Protein
    序列
    Leu25-Ser378
    产品特性
    Recombinant FITC-Labeled Human EGFRVIII Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu25-Ser378.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
    别名
    EGFRVIII (EGFRv3 产品)
    背景
    The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.
    分子量
    41.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
    NCBI登录号
    NP_001333870
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