EGFRviii Protein (AA 25-378) (His tag,FITC)
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- 抗原 See all EGFRviii (EGFRv3) products
- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-378
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EGFRviii protein is labelled with His tag,FITC.
- 产品特性
- FITC-Labeled Human EGFRvIII Protein, His Tag
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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EGFR vIII (EGFRv3) (AA 25-378) protein (His-Avi Tag,Biotin)
EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EGFR vIII (EGFRv3) protein (His-Avi Tag)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
EGFR vIII (EGFRv3) (AA 25-378) protein (FITC,His-Avi Tag)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
EGFR vIII (EGFRv3) (AA 25-378) protein (PE,His-Avi Tag)EGFRv3 宿主: 人 宿主: HEK-293 Cells Recombinant
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
- 别名
- EGFRvIII (EGFRv3 产品)
- 背景
- The epidermal growth factor receptor (EGFR, ErbB-1, HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. The type III EGF deletion-mutant receptor (EGFRvIII) is the most common mutation and was first identified in primary human glioblastoma tumors, EGFR gene amplification is correlated with the structural rearrangement of the gene. The EGFRvIII gene has an in-frame deletion of 801 base pairs, corresponding to exons 2-7 in the mRNA, resulting in the deletion of amino acids 30-297 in the extracellular domain and the generation of a glycine at the fusion point
- 分子量
- 40.5 kDa
- NCBI登录号
- NP_001333870
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