Angiotensin II Type-1 Receptor 蛋白
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- 抗原 See all Angiotensin II Type-1 Receptor (AGTR1) 蛋白
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
- 蛋白类型
- Synthetic
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human AGTR1 full length protein-synthetic nanodisc
- 产品特性
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product AGTR1 蛋白
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Angiotensin II Receptor, Type 1 (AGTR1) (AA 250-359) protein (GST tag)
AGTR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Angiotensin II Receptor, Type 1 (AGTR1) (AA 297-359), (Cytoplasmic Domain), (Cytosolic) protein (His tag)AGTR1 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
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- 应用备注
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- 说明
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
- 别名
- AGTR1 (AGTR1 产品)
- 别名
- AG2S Protein, AGTR1A Protein, AGTR1B Protein, AT1 Protein, AT1AR Protein, AT1B Protein, AT1BR Protein, AT1R Protein, AT2R1 Protein, AT2R1A Protein, AT2R1B Protein, HAT1R Protein, 1810074K20Rik Protein, AI551199 Protein, AT1a Protein, Agtr-1a Protein, Agtr1 Protein, Angtr-1a Protein, AT1A Protein, XAT-1 Protein, agtr1-A Protein, agtr1.2 Protein, AT1-R Protein, at1 Protein, AGTR1 Protein, Agtr-1b Protein, Angtr-1b Protein, agtr1 Protein, agtr1-a Protein, agtr1-b Protein, xAT Protein, angiotensin II receptor type 1 Protein, angiotensin II receptor, type 1a Protein, angiotensin II receptor type 1 S homeolog Protein, uncharacterized AGTR1 Protein, angiotensin II receptor, type 1b Protein, angiotensin II receptor type 1 L homeolog Protein, AGTR1 Protein, Agtr1a Protein, agtr1.S Protein, Agtr1 Protein, Agtr1b Protein, agtr1.L Protein
- 背景
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AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R
Description: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020] - 分子量
- The human full length AGTR1 protein has a MW of 40.9 kDa
- UniProt
- P30556
- 途径
- JAK/STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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