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Angiotensin II Type-1 Receptor Protein (Fc Tag)

AGTR1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491257
发货至: 中国
  • 抗原 See all Angiotensin II Type-1 Receptor (AGTR1) 蛋白
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This Angiotensin II Type-1 Receptor protein is labelled with Fc Tag.
    原理
    Recombinant Human AGTR1 Protein with C-terminal human Fc tag
    特异性
    AGTR1 (Met1-Ile27) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product AGTR1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    别名
    AGTR1 (AGTR1 产品)
    别名
    AG2S Protein, AGTR1A Protein, AGTR1B Protein, AT1 Protein, AT1AR Protein, AT1B Protein, AT1BR Protein, AT1R Protein, AT2R1 Protein, AT2R1A Protein, AT2R1B Protein, HAT1R Protein, 1810074K20Rik Protein, AI551199 Protein, AT1a Protein, Agtr-1a Protein, Agtr1 Protein, Angtr-1a Protein, AT1A Protein, XAT-1 Protein, agtr1-A Protein, agtr1.2 Protein, AT1-R Protein, at1 Protein, AGTR1 Protein, Agtr-1b Protein, Angtr-1b Protein, agtr1 Protein, agtr1-a Protein, agtr1-b Protein, xAT Protein, angiotensin II receptor type 1 Protein, angiotensin II receptor, type 1a Protein, angiotensin II receptor type 1 S homeolog Protein, uncharacterized AGTR1 Protein, angiotensin II receptor, type 1b Protein, angiotensin II receptor type 1 L homeolog Protein, AGTR1 Protein, Agtr1a Protein, agtr1.S Protein, Agtr1 Protein, Agtr1b Protein, agtr1.L Protein
    背景
    AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1RAngiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors.
    Description: This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020]
    分子量
    predicted molecular mass of 29.2 kDa after removal of the signal peptide. The apparent molecular mass of AGTR1-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P30556
    途径
    JAK/STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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