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LRP6 Protein (His tag)

LRP6 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491293
发货至: 中国
  • 抗原 See all LRP6 蛋白
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    资源
    • 6
    • 3
    • 1
    HEK-293 Cells
    标记
    This LRP6 protein is labelled with His tag.
    原理
    Recombinant Human LRP6 Protein with C-terminal 6xHis tag
    特异性
    LRP6 (Ala20-Ala1370) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product LRP6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    别名
    LRP6 (LRP6 产品)
    别名
    lrp6-A Protein, Xlrp6 Protein, adcad2 Protein, lrp6 Protein, LRP6 Protein, ADCAD2 Protein, C030016K15Rik Protein, Cd Protein, Gw Protein, LDL receptor related protein 6 Protein, LDL receptor related protein 6 L homeolog Protein, LDL receptor related protein 6 S homeolog Protein, low density lipoprotein receptor-related protein 6 Protein, low-density lipoprotein receptor-related protein 6 Protein, LRP6 Protein, lrp6.L Protein, lrp6.S Protein, lrp6 Protein, Lrp6 Protein, LOC590395 Protein
    背景
    ADCAD2, STHAG7
    Description: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands.
    Description: The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
    分子量
    predicted molecular mass of 153.1 kDa after removal of the signal peptide. The apparent molecular mass of LRP6-His is 130-250 kDa due to glycosylation.
    UniProt
    O75581
    途径
    WNT signaling, Tube Formation
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