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LRP6 Protein (AA 20-630) (Fc Tag)

LRP6 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6938849
发货至: 中国
  • 抗原 See all LRP6 蛋白
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 20-630
    宿主
    • 7
    • 3
    资源
    • 6
    • 3
    • 1
    HEK-293 Cells
    标记
    This LRP6 protein is labelled with Fc Tag.
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product LRP6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    储存条件
    -20 °C
  • 抗原
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    别名
    LRP-6 (LRP6 产品)
    别名
    lrp6-A Protein, Xlrp6 Protein, adcad2 Protein, lrp6 Protein, LRP6 Protein, ADCAD2 Protein, C030016K15Rik Protein, Cd Protein, Gw Protein, LDL receptor related protein 6 Protein, LDL receptor related protein 6 L homeolog Protein, LDL receptor related protein 6 S homeolog Protein, low density lipoprotein receptor-related protein 6 Protein, low-density lipoprotein receptor-related protein 6 Protein, LRP6 Protein, lrp6.L Protein, lrp6.S Protein, lrp6 Protein, Lrp6 Protein, LOC590395 Protein
    背景
    LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.
    分子量
    95.8 kDa
    NCBI登录号
    NP_002327
    途径
    WNT signaling, Tube Formation
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