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FZD7 Protein (Fc Tag)

FZD7 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491279
发货至: 中国
  • 抗原 See all FZD7 products
    FZD7 (Frizzled Family Receptor 7 (FZD7))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 2
    资源
    • 4
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This FZD7 protein is labelled with Fc Tag.
    原理
    Recombinant Human FZD7 Protein with N-terminal human Fc tag
    特异性
    HFc (Glu99-Ala330) FZD7 (Gln33-Arg254)
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    FZD7 (Frizzled Family Receptor 7 (FZD7))
    别名
    FZD7 (FZD7 产品)
    别名
    FzE3 Protein, Fz-7 Protein, Xfz7 Protein, frizzled-7 Protein, frizzled7 Protein, frz-7 Protein, frz7 Protein, fz7 Protein, fzd7-a Protein, fzd7-b Protein, fze3 Protein, Fz7 Protein, cFz-7 Protein, fb38g02 Protein, fc44b09 Protein, fz13 Protein, fz7a Protein, fz7b Protein, wu:fb38g02 Protein, wu:fc44b09 Protein, zg13 Protein, frizzled class receptor 7 Protein, frizzled class receptor 7 L homeolog Protein, frizzled class receptor 7b Protein, FZD7 Protein, fzd7.L Protein, fzd7 Protein, Fzd7 Protein, fzd7b Protein
    背景
    FzE3Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
    分子量
    predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FZD7 is 55-70 kDa due to glycosylation.
    UniProt
    O75084
    途径
    WNT signaling, Stem Cell Maintenance
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