FZD7 Protein (AA 33-185) (Fc Tag)
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- 抗原 See all FZD7 products
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 33-185
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FZD7 protein is labelled with Fc Tag.
- 序列
- AA 33-185
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 43.3 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >92 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- 抗原
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- 别名
- Frizzled-7 (FZD7 产品)
- 别名
- FzE3 Protein, Fz-7 Protein, Xfz7 Protein, frizzled-7 Protein, frizzled7 Protein, frz-7 Protein, frz7 Protein, fz7 Protein, fzd7-a Protein, fzd7-b Protein, fze3 Protein, Fz7 Protein, cFz-7 Protein, fb38g02 Protein, fc44b09 Protein, fz13 Protein, fz7a Protein, fz7b Protein, wu:fb38g02 Protein, wu:fc44b09 Protein, zg13 Protein, frizzled class receptor 7 Protein, frizzled class receptor 7 L homeolog Protein, frizzled class receptor 7b Protein, FZD7 Protein, fzd7.L Protein, fzd7 Protein, Fzd7 Protein, fzd7b Protein
- 背景
- Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.
- 分子量
- 43.3 kDa
- 途径
- WNT signaling, Stem Cell Maintenance
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