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IL18BP Protein (AA 28-207) (Biotin,His tag)

IL18BP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
产品编号 ABIN7454150
发货至: 中国
  • 抗原 See all IL18BP 蛋白
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    蛋白类型
    Recombinant
    产品特性
    AA 28-207
    宿主
    • 13
    • 6
    • 2
    • 2
    • 1
    Cynomolgus
    资源
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL18BP protein is labelled with Biotin,His tag.
    原理
    Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling)
    序列
    Thr28-Pro207
    产品特性
    Recombinant Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr28-Pro207.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 1.67 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL18BP 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    别名
    IL-18BP (IL18BP 产品)
    别名
    IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
    背景
    Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
    分子量
    21.14 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5UDJ4
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