Claudin 18.2 protein (His tag,Strep Tag)
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- 抗原
- Claudin 18.2
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Insect Cells
- 标记
- His tag,Strep Tag
- 原理
- Human Claudin-18.2 Protein, His,Twin-Strep Tag (Nanodisc)
- 序列
- Met 1 - Ala 200
- 产品特性
- Human Claudin-18.2, His,Twin-Strep Tag is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ala 200 (Accession # P56856-2).
- 内毒素水平
- 1.0 EU per μg
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Claudin 18.2 (AA 1-261) (Active) protein-VLP
宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Func, Imm, SPR Active
Claudin 18.2 (AA 1-261) (Active) protein-VLP (Biotin)宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Func, Imm, SPR Active
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- 说明
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This protein carries a polyhistidine tag at the N-terminus and a twin strep tag at the C-terminus. The protein has a calculated MW of 26.5 kDa.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 20 mM HEPES, 150 mM NaCl, pH 7.5
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- Claudin 18.2
- 别名
- Claudin-18.2
- 背景
- Synonyms:Claudin-18.2,CLDN18,Claudin-18,Description:Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on short-lived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells.
- 分子量
- 26.5 kDa
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