电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TNFRSF1B Protein (mFc Tag)

TNFRSF1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
产品编号 ABIN7275765
发货至: 中国
  • 抗原 See all TNFRSF1B 蛋白
    TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
    蛋白类型
    Recombinant
    宿主
    • 22
    • 11
    • 2
    • 2
    • 1
    资源
    • 15
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This TNFRSF1B protein is labelled with mFc Tag.
    序列
    Leu23-Asp257
    纯度
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human TNFR2 at 5μg/ml (100μl/Well). Dose response curve for Human TNF alpha, His Tag with the EC50 of 0.17μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product TNFRSF1B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
    别名
    TNFR2 (TNFRSF1B 产品)
    别名
    CD120b Protein, TBPII Protein, TNF-R-II Protein, TNF-R75 Protein, TNFBR Protein, TNFR1B Protein, TNFR2 Protein, TNFR80 Protein, p75 Protein, p75TNFR Protein, TNF-RII/TNFRSF1B Protein, TNFR-II Protein, TNFRSF1B Protein, TNF-R2 Protein, TNF-alphaR2 Protein, TNFRII Protein, TNFalpha-R2 Protein, Tnfr-1 Protein, Tnfr2 Protein, rank Protein, zgc:163064 Protein, TNF receptor superfamily member 1B Protein, tumor necrosis factor receptor superfamily, member 1b Protein, tumor necrosis factor receptor superfamily, member 1B Protein, TNFRSF1B Protein, Tnfrsf1b Protein, tnfrsf1b Protein
    背景
    CD120b, Etanercept, p75TBPII, p75TNFR, TNF RII, TNF-R2, TNF-R75, TNFR80, TNFRSF1B, TNFR2, TBPII, TNFBR, TNFR1B,Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.
    分子量
    51.5 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.
    UniProt
    P20333
    途径
    NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
You are here: