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SFRP2 Protein (AA 25-295) (His tag)

SFRP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7275651
发货至: 中国
  • 抗原 See all SFRP2 蛋白
    SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))
    蛋白类型
    Recombinant
    产品特性
    AA 25-295
    宿主
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    资源
    • 7
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This SFRP2 protein is labelled with His tag.
    原理
    Human SFRP2 Protein
    序列
    Leu25-Cys295
    产品特性
    Recombinant Human SFRP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu25-Cys295.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in 20 mM PBS, 100 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))
    别名
    SFRP2 (SFRP2 产品)
    别名
    frp-2 Protein, sarp1 Protein, sdf-5 Protein, sfrp-2 Protein, SFRP2 Protein, sfrp2 Protein, FRP-2 Protein, SARP1 Protein, SDF-5 Protein, AI851596 Protein, Sdf5 Protein, hm:zeh0225 Protein, zeh0225 Protein, zgc:153618 Protein, SFRP-2 Protein, secreted frizzled-related protein 2 Protein, secreted frizzled related protein 2 Protein, secreted frizzled-related protein 2 S homeolog Protein, secreted frizzled-related protein Protein, sfrp2 Protein, sfrp2 Protein, SFRP2 Protein, sfrp2.S Protein, LOAG_01461 Protein, Sfrp2 Protein
    背景
    As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in the Wnt signaling pathway, and the prognosis of CRC were not consistent. SFRP1, SFRP2, and WIF1 were frequently hypermethylated in CRC tumor tissues. It was apparent that the promoter hypermethylation of SFRP2 and co-hypermethylation of SFRP1 and SFRP2 might be considered as independent prognostic predictors for survival advantage of postoperative CRC patients.
    分子量
    32.4 kDa. Due to glycosylation, the protein migrates to 34-38 kDa based on Tris-Bis PAGE result.
    UniProt
    Q96HF1
    途径
    WNT signaling, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation
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