KREMEN1 Protein (AA 21-392) (Fc Tag)
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- 抗原 See all KREMEN1 蛋白
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-392
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KREMEN1 protein is labelled with Fc Tag.
- 原理
- Human Kremen-1 Protein
- 序列
- Arg21-Thr392
- 产品特性
- Recombinant Human Kremen-1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Arg21-Thr392.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 310-391) protein (GST tag)
KREMEN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 21-392) protein (His tag)Crystallography grade KREMEN1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 21-392) protein (His tag)Crystallography grade KREMEN1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 20-473) protein (rho-1D4 tag)Crystallography grade KREMEN1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 20-473) protein (rho-1D4 tag)Crystallography grade KREMEN1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 21-392) (Active) protein (Fc Tag)KREMEN1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Kringle Containing Transmembrane Protein 1 (KREMEN1) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)KREMEN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- 别名
- Kremen-1 (KREMEN1 产品)
- 别名
- KREMEN1 Protein, krm1 Protein, kremen Protein, kremem1 Protein, KREMEN Protein, KRM1 Protein, AV002070 Protein, Kremen Protein, Krm1 Protein, si:ct737139.1 Protein, si:dkeyp-7c9.1 Protein, kringle containing transmembrane protein 1 Protein, kringle containing transmembrane protein 1 S homeolog Protein, KREMEN1 Protein, kremen1 Protein, Kremen1 Protein, kremen1.S Protein
- 背景
- KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.
- 分子量
- 67.6 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
- 途径
- WNT signaling
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