KREMEN1 Protein (AA 21-392) (Fc Tag)
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- 抗原 See all KREMEN1 蛋白
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 21-392
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KREMEN1 protein is labelled with Fc Tag.
- 产品特性
- Human Kremen-1 protein, Fc Tag
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KREMEN1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- 别名
- KREMEN1 (KREMEN1 产品)
- 别名
- KREMEN1 Protein, krm1 Protein, kremen Protein, kremem1 Protein, KREMEN Protein, KRM1 Protein, AV002070 Protein, Kremen Protein, Krm1 Protein, si:ct737139.1 Protein, si:dkeyp-7c9.1 Protein, kringle containing transmembrane protein 1 Protein, kringle containing transmembrane protein 1 S homeolog Protein, KREMEN1 Protein, kremen1 Protein, Kremen1 Protein, kremen1.S Protein
- 背景
- Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).
- 分子量
- 67.4 kDa
- 途径
- WNT signaling
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