IGF1R Protein (AA 31-932) (His-Avi Tag)
-
- 抗原 See all IGF1R 蛋白
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-932
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This IGF1R protein is labelled with His-Avi Tag.
- 原理
- Human IGF1R/CD221 Protein
- 序列
- Glu31-Asn932
- 产品特性
- Recombinant Human IGF1R/CD221 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu31-Asn932.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IGF1R, His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-IGF1R Antibody, hFc Tag with the EC50 of 54.1ng/ml determined by ELISA. See testing image for detail.
-
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-932) protein (His-Avi Tag,Biotin)
IGF1R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 959-1367) (Active) protein (GST tag)IGF1R 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 954-1367) (Active) protein (His-GST)IGF1R 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 31-932) (Active) protein (His tag)IGF1R 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 741-935) protein (His-IF2DI Tag)IGF1R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 761-870) protein (GST tag)IGF1R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 741-935) protein (His-DYKDDDDK-Strep II Tag)IGF1R 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 741-935) protein (His tag)Crystallography grade IGF1R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 742-936) protein (His tag)Crystallography grade IGF1R 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 961-1373) protein (His tag)Crystallography grade IGF1R 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- 别名
- IGF1R (IGF1R 产品)
- 别名
- CMT2N Protein, CD221 Protein, IGFIR Protein, IGFR Protein, JTK13 Protein, IGFIRC Protein, IGFR1 Protein, IGF-1R Protein, IGF1R Protein, DKFZp469I0618 Protein, igf-1r Protein, xIGF-1R Protein, xIGFR Protein, xigf1r Protein, A330103N21Rik Protein, D930020L01 Protein, hyft Protein, igf-ir Protein, IGF-IR Protein, IGF-IRb Protein, wu:fb03h06 Protein, IGF-IRa Protein, sb:eu1090 Protein, wu:fi20b10 Protein, alanyl-tRNA synthetase Protein, insulin like growth factor 1 receptor Protein, insulin-like growth factor 1 receptor Protein, insulin-like growth factor 1 Protein, insulin-like growth factor I receptor Protein, insulin like growth factor 1 receptor S homeolog Protein, insulin-like growth factor 1b receptor Protein, insulin-like growth factor 1a receptor Protein, AARS Protein, IGF1R Protein, Igf1r Protein, igf1r Protein, Igf1 Protein, LOC780503 Protein, LOC100136427 Protein, igf1r.S Protein, igf1rb Protein, igf1ra Protein
- 背景
- The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target.
- 分子量
- 105.8 kDa (alpha subunit) and 23 kDa (beta subunit). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
- UniProt
- P08069
- 途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
-
