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IFNGR1 Protein (AA 18-245) (Fc Tag)

IFNGR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274846
发货至: 中国
  • 抗原 See all IFNGR1 蛋白
    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
    蛋白类型
    Recombinant
    产品特性
    AA 18-245
    宿主
    • 12
    • 11
    资源
    • 7
    • 6
    • 5
    • 4
    • 1
    HEK-293 Cells
    标记
    This IFNGR1 protein is labelled with Fc Tag.
    原理
    Human IFN gamma R1/IFNGR1 Protein
    序列
    Glu18-Gly245
    产品特性
    Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human Human IFN gamma, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 13.0ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
    别名
    IFN gamma R1 (IFNGR1 产品)
    别名
    CD119 Protein, IFNGR Protein, IFN-gammaR Protein, Ifgr Protein, Ifngr Protein, Nktar Protein, IFNGR1 Protein, MGC129098 Protein, ifngr1 Protein, MGC194858 Protein, MGC194873 Protein, zgc:194858 Protein, cd119 Protein, ifngr Protein, DKFZp469K1232 Protein, interferon gamma receptor 1 Protein, cytokine receptor family member B17 Protein, IFNGR1 Protein, Ifngr1 Protein, crfb17 Protein, ifngr1 Protein
    背景
    IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
    分子量
    52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
    途径
    Interferon-gamma Pathway
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