IFNGR1 Protein (Fc Tag)
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- 抗原 See all IFNGR1 蛋白
- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This IFNGR1 protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse IFNGR1/CD119 Protein (Fc Tag)(Active)
- 序列
- Met 1-Asp 253
- 产品特性
- A DNA sequence encoding the mouse IFNGR1 (P15261) extracellular domain (Met 1-Asp 253) was fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized mouse IFNG-His at 10 μg/ml (100 μl/well) can bind mouse IFNGR1-Fc. The EC50 of IFNGR1-Fc is 58.2-135.9 ng/ml.
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- Discover our top product IFNGR1 蛋白
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Interferon gamma Receptor 1 (IFNGR1) (AA 18-245) protein (Fc Tag)
IFNGR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interferon gamma Receptor 1 (IFNGR1) protein (His tag)IFNGR1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma Receptor 1 (IFNGR1) protein (Fc Tag)IFNGR1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma Receptor 1 (IFNGR1) (Active) protein (His tag)IFNGR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Interferon gamma Receptor 1 (IFNGR1) (AA 267-489) protein (His tag)Crystallography grade IFNGR1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 18-245) protein (His tag)Crystallography grade IFNGR1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 26-254) protein (His tag)Crystallography grade IFNGR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 276-477) protein (His tag)Crystallography grade IFNGR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 18-489) protein (rho-1D4 tag)Crystallography grade IFNGR1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon gamma Receptor 1 (IFNGR1) (AA 26-477) protein (rho-1D4 tag)Crystallography grade IFNGR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
- 别名
- IFNGR1/CD119 (IFNGR1 产品)
- 别名
- CD119 Protein, IFNGR Protein, IFN-gammaR Protein, Ifgr Protein, Ifngr Protein, Nktar Protein, IFNGR1 Protein, MGC129098 Protein, ifngr1 Protein, MGC194858 Protein, MGC194873 Protein, zgc:194858 Protein, cd119 Protein, ifngr Protein, DKFZp469K1232 Protein, interferon gamma receptor 1 Protein, cytokine receptor family member B17 Protein, IFNGR1 Protein, Ifngr1 Protein, crfb17 Protein, ifngr1 Protein
- 背景
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Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.
Synonym: CD119;Ifgr;IFN-gammaR;Ifngr;Nktar
- 分子量
- 53 kDa
- UniProt
- P15261
- 途径
- Interferon-gamma Pathway
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